Medication Guide
Comprehensive overview of all weight loss medications available through US telehealth providers
Wegovy (Injection)
GLP-1 Injection (Brand-Name)✓ FDA ApprovedWeekly self-injection. Gold standard FDA-approved GLP-1 for weight loss. Average 15% body weight loss in clinical trials.
Wegovy (Oral Pill)
GLP-1 Oral Pill (Brand-Name)✓ FDA ApprovedDaily oral pill. FDA approved January 2026. Same active ingredient as Wegovy injection but taken by mouth. Starting at $149/mo via NovoCare.
Zepbound
GLP-1 Injection (Brand-Name)✓ FDA ApprovedWeekly injection. Dual GIP/GLP-1 agonist. Clinical trials show up to 22% body weight loss — the highest of any approved medication.
Ozempic
GLP-1 Injection (Brand-Name)✓ FDA ApprovedWeekly injection. FDA-approved for diabetes; widely prescribed off-label for weight loss. Same active ingredient as Wegovy.
Saxenda
GLP-1 Injection (Brand-Name)✓ FDA ApprovedDaily injection. Older GLP-1 medication. Less effective than semaglutide or tirzepatide but FDA-approved for weight loss.
Compounded Semaglutide
Compounded Injection⚠ Not FDA-ApprovedCompounded version of semaglutide from licensed 503B pharmacies. Not FDA-approved but significantly cheaper. Availability may be limited as FDA shortage status changes.
Compounded Tirzepatide
Compounded Injection⚠ Not FDA-ApprovedCompounded version of tirzepatide. Significantly cheaper than brand-name Zepbound. Check current FDA shortage status for availability.
Compounded Semaglutide (Oral)
Compounded Oral/Sublingual⚠ Not FDA-ApprovedOral/sublingual compounded semaglutide. Newest and most affordable option. Available as pills, lozenges, or sublingual drops.
Contrave
Traditional Weight Loss Pill✓ FDA ApprovedDaily oral pill. FDA-approved combination of naltrexone and bupropion. Works on brain reward pathways to reduce cravings. Average 5-8% weight loss.
Qsymia
Traditional Weight Loss Pill✓ FDA ApprovedDaily oral pill. FDA-approved combination of phentermine and topiramate. Appetite suppressant. Average 8-10% weight loss.
About Compounded Medications
Compounded semaglutide and tirzepatide are made by licensed 503A and 503B compounding pharmacies. They are not FDA-approved and are not the same as brand-name Wegovy, Ozempic, or Zepbound. The FDA permitted compounding of these drugs during shortage periods. As shortages resolve, the FDA may restrict compounded versions.
Always consult a licensed healthcare provider before starting any weight loss medication. This guide is for informational purposes only and does not constitute medical advice.