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comparisons 5 min readApril 1, 2026
Wegovy vs Zepbound: Which Is Cheaper in 2026?
A detailed price comparison of the two leading FDA-approved GLP-1 weight loss injections across all major US telehealth platforms.
wegovy zepbound semaglutide tirzepatide price comparison
Wegovy vs Zepbound: The 2026 Price Breakdown
Both Wegovy (semaglutide) and Zepbound (tirzepatide) are FDA-approved GLP-1 receptor agonists for chronic weight management.
Brand-Name Prices
Wegovy retails at approximately $1,349/month without insurance. Through NovoCare, eligible patients can pay as little as $0-$25/month with commercial insurance.
Zepbound retails at approximately $1,059/month without insurance. LillyDirect offers self-pay vials starting at $349/month for the 2.5mg dose.
Compounded Alternatives
Verdict
For brand-name medications, Zepbound is cheaper at self-pay rates. For compounded options, semaglutide wins on price.
Prices sourced from provider websites as of April 2026. Not medical advice.